Synthesis of Spirocyclohexanone Ring Containing Thiazolidine Nucleus: A Regioselective Approach
| Autor: | Vijay Suryanarayan, Madhukar S. Chande |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Addition reaction
010405 organic chemistry Thiazolidine Regioselectivity General Chemistry General Medicine 010402 general chemistry Ring (chemistry) 01 natural sciences Medicinal chemistry Dieckmann condensation 0104 chemical sciences chemistry.chemical_compound chemistry Michael reaction Organic chemistry Acrylonitrile Methyl acrylate Derivative (chemistry) |
| Zdroj: | ChemInform. 36 |
| ISSN: | 1522-2667 0931-7597 |
| Popis: | The paper highlights the Michael addition reactions of 2-arylimino-3-aryl-thiazolidin-4-one 1 with acceptors like methyl acrylate and acrylonitrile to furnish the diadducts 5 and 8. Dieckmann condensation of 5 affords the spirocyclohexanone derivative. Also discussed is the interaction of 1 with 1,5-diarylpenta-1,4-dien-3-ones 9. |
| Databáze: | OpenAIRE |
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