Systemic Inflammatory Response Syndrome, Organ Failure, and Outcome in Critically Ill Obstetric Patients Treated in an ICU
| Autor: | Bethany Green, Bekele Afessa, Isaac Delke, Kathryn A. Koch |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Pulmonary and Respiratory Medicine medicine.medical_specialty ARDS Adolescent Critical Care Multiple Organ Failure Critical Care and Intensive Care Medicine law.invention Postoperative Complications Pregnancy Risk Factors law Internal medicine Severity of illness medicine Humans Hospital Mortality Intensive care medicine APACHE Retrospective Studies Respiratory Distress Syndrome Eclampsia Cesarean Section business.industry Mortality rate Infant Newborn Retrospective cohort study Puerperal Disorders medicine.disease Intensive care unit Systemic Inflammatory Response Syndrome Pregnancy Complications Survival Rate Systemic inflammatory response syndrome Respiratory failure Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Chest. 120:1271-1277 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.120.4.1271 |
| Popis: | Study objectives To determine the incidence of systemic inflammatory response syndrome (SIRS) and organ failure and to describe the outcomes in critically ill obstetric patients who have been treated in medical ICUs. Design Retrospective review. Setting A multidisciplinary ICU at a tertiary-care institution. Methods We collected data on 74 obstetric patients who were admitted consecutively to the ICU from January 1991 through December 1998. Acute physiology and chronic health evaluation (APACHE) II scores were calculated. A p value Measurements and results Fifty-eight percent of patients were admitted to the ICU postpartum. Their mean (± SD) age was 25.9 ± 7.0 years, and 64% were African American and 34% were white. Fifty percent had preexisting medical conditions. Their mean APACHE II score was 14.0 ± 5.9, and their predicted mortality rate was 17.6%. The most common reason for admission was respiratory insufficiency. Preeclampsia was present in 38% of patients, and hemolytic anemia, elevated liver enzymes, and low platelet count syndrome were present in 7% of patients. SIRS developed in 59% of patients. Patients with SIRS had longer ICU stays (p = 0.0008). Organ failure developed in 65% of patients, and ARDS developed in 15% of patients. Invasive mechanical ventilation was required in 45% of patients, and pulmonary artery catheterization was required in 35% of patients. The in-hospital mortality rate was 2.7%. There were five spontaneous abortions and eight perinatal deaths. Conclusions The most common reason for admission to the ICU of critically ill obstetric patients was respiratory failure. Despite the severity of illness and the development of SIRS and organ failure in most patients, the mortality rate was low. |
| Databáze: | OpenAIRE |
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