Glyprolines and semax prevent stress-induced microcirculatory disturbances in the mesentery
| Autor: | B. A. Umarova, G. E. Samonina, L. Ts. Sanzhieva, Elena A. Smirnova, T. V. Lelekova, G. N. Kopylova |
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| Rok vydání: | 2004 |
| Předmět: |
Male
medicine.medical_specialty Proline Semax Hemorrhage General Biochemistry Genetics and Molecular Biology Microcirculation Norepinephrine (medication) Immobilization Norepinephrine Adrenocorticotropic Hormone Stress Physiological Internal medicine medicine Animals Mesentery business.industry Stress induced General Medicine Anatomy Blood flow Peptide Fragments Rats Endocrinology medicine.anatomical_structure Lymphatic system Regional Blood Flow business Oligopeptides medicine.drug |
| Zdroj: | Bulletin of experimental biology and medicine. 136(5) |
| ISSN: | 0007-4888 |
| Popis: | One-hour immobilization stress considerably disturbed microcirculation in the mesentery: blood flow in small mesenteric vessels decreased or stopped and numerous hemorrhages appeared. Lymphatic vessels lost spontaneous activity and did not respond to norepinephrine. Administration of Semax and glyprolines 1 h before stress decreased the severity of stress-induced microcirculatory disturbances. PGP and GP were most effective in this respect. |
| Databáze: | OpenAIRE |
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