Assessment of CT dose to the fetus and pregnant female patient using patient-specific computational models
| Autor: | Pierre-Alexandre Alois Poletti, Tianwu Xie, Habib Zaidi, Christoph D. Becker, Alexandra Platon |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Tomography X-Ray Computed/methods Effective dose (radiation) MULTIDETECTOR CT 030218 nuclear medicine & medical imaging Fetus/radiation effects 0302 clinical medicine Radiation dosimetry Pregnancy Radiometry/methods GESTATION PHANTOM reproductive and urinary physiology Neuroradiology RISK medicine.diagnostic_test Phantoms Imaging Ultrasound Gestational age Foetal dose Interventional radiology General Medicine DOSIMETRY Pregnant female models 030220 oncology & carcinogenesis Absorbed dose Pregnancy Complications/diagnostic imaging CHEST Female Radiology CONCEPTUS Monte Carlo Method CT Radiography Abdominal medicine.medical_specialty Gestational Age Radiography Abdominal/methods Radiation Dosage RADIATION-EXPOSURE ddc:616.0757 Risk Assessment Imaging phantom 03 medical and health sciences Fetus medicine Dosimetry Humans Radiology Nuclear Medicine and imaging Computer Simulation Radiometry Monte Carlo simulation FETAL Retrospective Studies business.industry SCANNERS Pregnancy Complications business Tomography X-Ray Computed |
| Zdroj: | European Radiology, Vol. 28, No 3 (2018) pp. 1054-1065 European Radiology, 28(3), 1054-1065. SPRINGER Xie, T, Poletti, P-A, Platon, A, Becker, C D & Zaidi, H 2018, ' Assessment of CT dose to the fetus and pregnant female patient using patient-specific computational models ', European Radiology, vol. 28, no. 3, pp. 1054–1065 . https://doi.org/10.1007/s00330-017-5000-z |
| ISSN: | 1432-1084 0938-7994 |
| DOI: | 10.1007/s00330-017-5000-z |
| Popis: | This work provides detailed estimates of the foetal dose from diagnostic CT imaging of pregnant patients to enable the assessment of the diagnostic benefits considering the associated radiation risks. To produce realistic biological and physical representations of pregnant patients and the embedded foetus, we developed a methodology for construction of patient-specific voxel-based computational phantoms based on existing standardised hybrid computational pregnant female phantoms. We estimated the maternal absorbed dose and foetal organ dose for 30 pregnant patients referred to the emergency unit of Geneva University Hospital for abdominal CT scans. The effective dose to the mother varied from 1.1 mSv to 2.0 mSv with an average of 1.6 mSv, while commercial dose-tracking software reported an average effective dose of 1.9 mSv (range 1.7–2.3 mSv). The foetal dose normalised to CTDIvol varies between 0.85 and 1.63 with an average of 1.17. The methodology for construction of personalised computational models can be exploited to estimate the patient-specific radiation dose from CT imaging procedures. Likewise, the dosimetric data can be used for assessment of the radiation risks to pregnant patients and the foetus from various CT scanning protocols, thus guiding the decision-making process. • In CT examinations, the absorbed dose is non-uniformly distributed within foetal organs. • This work reports, for the first time, estimates of foetal organ-level dose. • The foetal brain and skeleton doses present significant correlation with gestational age. • The conceptus dose normalised to CTDI vol varies between 0.85 and 1.63. • The developed methodology is adequate for patient-specific CT radiation dosimetry. |
| Databáze: | OpenAIRE |
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