Direct Transport to a Percutaneous Cardiac Intervention Center and Outcomes in Patients With Out-of-Hospital Cardiac Arrest

Autor: Carolina Malta Hansen, Christopher B. Fordyce, Emil L. Fosbøl, Claire C. Corbett, Ying Xian, Benjamin S. Abella, David Pearson, Clark Tyson, Christopher B. Granger, James G. Jollis, Bryan McNally, Lisa Monk, Benjamin Strauss, Kristian Kragholm, Matthew E. Dupre
Rok vydání: 2017
Předmět:
Male
Emergency Medical Services
medicine.medical_specialty
Time Factors
medicine.medical_treatment
030204 cardiovascular system & hematology
Return of spontaneous circulation
Coronary Angiography
Logistic regression
Risk Assessment
Time-to-Treatment
Odds
Electrocardiography
03 medical and health sciences
Percutaneous Coronary Intervention
0302 clinical medicine
Risk Factors
North Carolina
Odds Ratio
Journal Article
Emergency medical services
Humans
Medicine
Hospital Mortality
Registries
Cardiopulmonary resuscitation
Aged
Chi-Square Distribution
Delivery of Health Care
Integrated

business.industry
030208 emergency & critical care medicine
Odds ratio
Middle Aged
Cardiopulmonary Resuscitation
Patient Discharge
Confidence interval
Surgery
Logistic Models
Transportation of Patients
Treatment Outcome
Multivariate Analysis
Conventional PCI
Emergency medicine
Female
Cardiology and Cardiovascular Medicine
business
Out-of-Hospital Cardiac Arrest
Zdroj: Sørensen, K D K, Malta Hansen, C, Dupre, M E, Xian, Y, Strauss, B, Tyson, C, Monk, L, Corbett, C, Fordyce, C B, Pearson, D A, Fosbøl, E L, Jollis, J G, Abella, B S, McNally, B & Granger, C B 2017, ' Direct Transport to a Percutaneous Cardiac Intervention Center and Outcomes in Patients With Out-of-Hospital Cardiac Arrest ', Circulation: Cardiovascular Quality and Outcomes, vol. 10, no. 6, e003414 . https://doi.org/10.1161/CIRCOUTCOMES.116.003414
ISSN: 1941-7705
1941-7713
Popis: Background— Practice guidelines recommend regional systems of care for out-of-hospital cardiac arrest. However, whether emergency medical services should bypass nonpercutaneous cardiac intervention (non-PCI) facilities and transport out-of-hospital cardiac arrest patients directly to PCI centers despite longer transport time remains unknown. Methods and Results— Using the Cardiac Arrest Registry to Enhance Survival with geocoding of arrest location, we identified out-of-hospital cardiac arrest patients with prehospital return of spontaneous circulation and evaluated the association between direct transport to a PCI center and outcomes in North Carolina during 2012 to 2014. Destination hospital was classified according to PCI center status (catheterization laboratory immediately accessible 24/7). Inverse probability-weighted logistic regression accounting for age, sex, emergency medical services response time, clustering of county, transport time to nearest PCI center, initial heart rhythm, and prehospital ECG information was performed. Of 1507 patients with prehospital return of spontaneous circulation, 1359 (90.2%) were transported to PCI centers, of whom 873 (57.9%) bypassed the nearest non-PCI hospital and 148 (9.8%) were transported to non-PCI hospitals. Discharge survival was higher among those transported to PCI centers (33.5% versus 14.6%; adjusted odds ratio, 2.47; 95% confidence interval, 2.08–2.92). Compared with patients taken to non-PCI hospitals, odds of survival were higher for patients taken to the nearest hospital with PCI center status (odds ratio, 3.07; 95% confidence interval, 1.90–4.97) and for patients bypassing closer hospitals to PCI centers (odds ratio, 3.02; 95% confidence interval, 2.01–4.53). Adjusted survival remained significantly better across transport times of 1 to 5, 6 to 10, 11 to 20, 21 to 30, and >30 minutes. Conclusions— Direct transport to a PCI center is associated with better outcomes for out-of-hospital cardiac arrest patients, even when bypassing nearest hospital and regardless of transport time.
Databáze: OpenAIRE