Tuberculosis treatment delay and nosocomial exposure remain important risks for patients undergoing regular hemodialysis
| Autor: | Yu Chun Yen, Tzu Yun Yu, Yuh Mou Sue, Chih Hsin Lee, Michael Lu, Ming Chih Yu, Han Lin Hsu, Jun Fu Zhang, Yi Jun Liu |
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| Rok vydání: | 2022 |
| Předmět: |
Adult
Microbiology (medical) Pediatrics medicine.medical_specialty Tuberculosis medicine.medical_treatment Time-to-Treatment End stage renal disease Renal Dialysis Diabetes mellitus medicine Humans Immunology and Allergy Infection control Tuberculosis Pulmonary Index case Cross Infection General Immunology and Microbiology business.industry Incidence (epidemiology) General Medicine Odds ratio medicine.disease Infectious Diseases Cough Case-Control Studies Kidney Failure Chronic Hemodialysis business |
| Zdroj: | Journal of Microbiology, Immunology and Infection. 55:926-934 |
| ISSN: | 1684-1182 |
| DOI: | 10.1016/j.jmii.2021.08.011 |
| Popis: | BACKGROUND AND OBJECTIVE Studies have reported an increased tuberculosis (TB) incidence among patients with end-stage renal disease (ESRD). This nationwide nested Case-control study investigated the risk of active TB due to nosocomial exposure and its correlation with the delay in TB treatment in hemodialysis patients. METHODS Adult (aged ≥20 years) patients with incident ESRD over 2000-2010 were identified from Taiwan National Health Insurance Research Database; 2331 patients with incident active TB (Case) were matched with 11,655 patients without TB (control) by age, sex, year of ESRD onset, Charlson comorbidity index, chronic obstructive pulmonary disease, and diabetes mellitus, at a 1:5 case-to-control ratio. RESULTS Compared with the control group, the Case group had greater nosocomial exposure to index patients with pulmonary TB (2.36 vs. 0.11 month of exposure, p |
| Databáze: | OpenAIRE |
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