Investigation of the SOS response of Escherichia coli after gamma-irradiation by means of the SOS chromotest
| Autor: | V. Drasil, M.M. Ogievetskaya, Evgeny Krasavin, S. Kozubek, J. Soska |
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| Rok vydání: | 1990 |
| Předmět: |
Time Factors
DNA Repair Health Toxicology and Mutagenesis genetic processes Cell γ irradiation medicine.disease_cause Microbiology chemistry.chemical_compound Genetics medicine Escherichia coli SOS response SOS Response Genetics Molecular Biology Chemistry biochemical phenomena metabolism and nutrition Alkaline Phosphatase beta-Galactosidase Molecular biology SOS chromotest enzymes and coenzymes (carbohydrates) medicine.anatomical_structure Gamma Rays bacteria Alkaline phosphatase DNA DNA Damage |
| Zdroj: | Mutation research. 230(1) |
| ISSN: | 0027-5107 |
| Popis: | The kinetics of SOS system induction in Escherichia coli PQ37 cell by γ-irradiation has been studied by the SOS chromotest technique. It was shown that the synthesis of constitutive alkaline phosphatase is not immediately stopped in cells that suffered lethal damages from γ-irradiation. The production of DNA damages inducing the SOS system was 0.021/Gy per genome. The SOS system was switched off approximately 200 min after γ-irradiation. A correction is proposed to the calculation of the SOS system induction factor. |
| Databáze: | OpenAIRE |
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