Clinical, Physiologic, and Pathologic Evidence for Vagus Dysfunction in a Case of Traumatic Brain Injury
| Autor: | Khang-cheng Ho, Gary Ludwig, Andrew J. Haig |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Traumatic brain injury Blood Pressure Autopsy Quadriplegia Lesion Central nervous system disease Fatal Outcome Heart Rate medicine Humans Gastric emptying business.industry Vagus Nerve Pulmonary edema medicine.disease Cranial Nerve Diseases Dorsal motor nucleus Brain Injuries Anesthesia Nerve tract medicine.symptom business |
| Zdroj: | The Journal of Trauma: Injury, Infection, and Critical Care. 40:441-444 |
| ISSN: | 1079-6061 |
| Popis: | A trauma victim with locked-in syndrome demonstrated severely decreased bowel sounds, intact response to suppository, and elevated, but unchanging pulse. Absent cardiac response to tracheal suctioning, high gastric residual volumes, and pulmonary edema in response to a urecholine challenge demonstrated dysfunction in the autonomic system. Symptoms persisted for 2 1/2 years until death. At autopsy, asymmetric bilateral involvement of the dorsal motor nucleus of the vagus and of the nerve tract in the medulla were demonstrated. In contrast, a control subject with locked-in syndrome caused by a stroke did not demonstrate these phenomenon. In trauma patients with delayed gastric emptying, measurement of the heart rate response to deep suctioning may lead to the diagnosis of this vagus dysfunction syndrome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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