Circumpapillary and macular vessel density assessment by optical coherence tomography angiography in eyes with temporal hemianopia from chiasmal compression. Correlation with retinal neural and visual field loss
Autor: | Mario R Monteiro, Leonardo Provetti Cunha, Leandro Cabral Zacharias, Rony Carlos Preti, Ana Claudia F. Suzuki |
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Rok vydání: | 2019 |
Předmět: |
Retinal Ganglion Cells
medicine.medical_specialty genetic structures Article Retina Correlation chemistry.chemical_compound Nerve Fibers Vessel density Atrophy Ophthalmology medicine Humans Receiver operating characteristic business.industry Angiography Retinal medicine.disease eye diseases Ganglion Cross-Sectional Studies medicine.anatomical_structure chemistry Optic nerve Hemianopsia Visual Field Tests Visual Fields business Tomography Optical Coherence |
Zdroj: | Eye (Lond) |
ISSN: | 1476-5454 0950-222X |
DOI: | 10.1038/s41433-019-0564-2 |
Popis: | AIMS: To compare the circumpapillary and macular vessel density (cpVD/mVD) of eyes with temporal visual field (VF) defect and band atrophy (BA) of the optic nerve and normal controls using OCTA and to verify the association of VD parameters with circumpapillary retinal nerve fibre layer (cpRNFL) thickness, macular ganglion cell complex (mGCC) thickness and VF loss. METHODS: Thirty-three eyes of 26 patients with BA and 42 eyes of 22 age-matched normal controls underwent OCT + OCTA scanning. cpVD and cpRNFL were expressed as average and sector measurements. mVD and mGCC were calculated as averages and in quadrants and hemiretinas. VF loss was estimated using the 24-2 and the 10-2 protocols. Generalized estimated equation models were used for comparisons and area under the receiver operating characteristics (AROC) were calculated. RESULTS: Compared with controls, BA eyes displayed smaller average cpVD and mVD values (p |
Databáze: | OpenAIRE |
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