Mimic of malignancy: delineating IgG4-related disease and lymphoma
| Autor: | Nicholas Hornstein, Amir A Razmjou, Monica El-Masry, Ari Weinreb |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Lymphoma Lymphadenopathy Case Report Disease Malignancy 03 medical and health sciences 0302 clinical medicine Internal medicine parasitic diseases medicine Humans skin and connective tissue diseases Bilateral ureters Aged 030203 arthritis & rheumatology integumentary system Retroperitoneal mass business.industry fungi General Medicine medicine.disease Rheumatology Immunoglobulin G 030220 oncology & carcinogenesis Concomitant IgG4-related disease Immunoglobulin G4-Related Disease Radiology Neoplasm Recurrence Local business |
| Zdroj: | BMJ Case Rep |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2020-237466 |
| Popis: | Here, we describe the case of a 74-year-old man who was incidentally found to have a hepatic lesion during routine screening. Additional diagnostic studies demonstrated elevated IgG4 levels, IgG4 plasma cell-predominant lymphadenopathy and an inflammatory retroperitoneal mass encasing the bilateral ureters and the aorta. Given the concurrence of a lymphomatous process and IgG4-related disease (IgG4-RD), a multidisciplinary approach was required to determine whether targeting the lymphoma or IgG4-RD would be most efficacious. Discussions led to the decision to target treatment against IgG4-RD with systemic glucocorticoids, and subsequent imaging showed resolution of all lesions. To date, the patient remains symptom-free and has not experienced recurrence of his disease. This case highlights the importance of multidisciplinary care and the challenge inherent in targeting treatment between IgG4-RD and a concomitant lymphomatous process. |
| Databáze: | OpenAIRE |
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