New algorithm for corneal densitometry assessment based on anterior segment optical coherence tomography
| Autor: | Carlos Rocha de Lossada, Jorge Peraza-Nieves, Irene Blanco-Domínguez, Tian Qiao Zhang, Xiao Yu Wang, Afredo Manuel Adán-Civiera, Anil Rahul Rachwani |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
genetic structures Concentric Cornea Young Adult Optical coherence tomography medicine Humans Aged Aged 80 and over medicine.diagnostic_test business.industry Corneal Topography Mean age Middle Aged eye diseases Healthy Volunteers Ophthalmology medicine.anatomical_structure sense organs Tomography Densitometry business Algorithm Algorithms Tomography Optical Coherence |
| Zdroj: | Eye (London, England). 36(8) |
| ISSN: | 1476-5454 |
| Popis: | PURPOSE To describe a new algorithm to measure corneal densitometry based on images obtained by swept source anterior segment ocular coherence tomography (SS-AS-OCT) and establish standard densitometry values in a group of normal eyes. METHODS A total of 111 healthy participants (195 eyes) were enrolled in this study. Using a MATLAB designed algorithm, the cornea was segmented into three layers: anterior, posterior and mid-stroma, and it was divided into two concentric areas, 0-2 and 2-4 mm, resulting in nine areas for the analysis. The mean corneal densitometry values were calculated and expressed as grayscale units (GSU). RESULTS The mean age was 57 years (range 22-87), with 100 (51.3%) right eyes and 95 (48.7%) left eyes. The total corneal densitometry was 86.9 ± 12.1 GSU. The mid-stroma layer had the highest densitometry values, 87.4 ± 12.1 GSU, and the anterior layer had the lowest values, 81.9 ± 14.2 GSU. Densitometry differences between the anterior layer and the mid-stroma layer (P |
| Databáze: | OpenAIRE |
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