Characterization Across a Dispersity: Polymer Mass Spectrometry in the Second Dimension
| Autor: | Mark P. Barrow, Sean H. Ellacott, Bryan P. Marzullo, Andrew Kerr, Tomos E. Morgan, Johanna Paris, Maria A. van Agthoven, Sébastien Perrier, Christopher A. Wootton, Peter B. O’Connor, Anthony W. T. Bristow |
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| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
Electron-capture dissociation Chemistry Polyacrylamide Dispersity Polymer Tandem mass spectrometry Mass spectrometry Characterization (materials science) chemistry.chemical_compound Fragmentation (mass spectrometry) Chemical engineering Structural Biology Spectroscopy |
| Zdroj: | Journal of the American Society for Mass Spectrometry. 32(8) |
| ISSN: | 1879-1123 |
| Popis: | Due to the natural dispersity that is present in synthetic polymers, an added complexity is always present in the analysis of polymeric species. Tandem mass spectrometry analysis requires the isolation of individual precursors before a fragmentation event to allow the unambiguous characterization of these species and is not viable at certain levels of complexity due to achievable isolation widths. Two-dimensional mass spectrometry (2DMS) fragments ions and correlates fragments with their corresponding precursors without the need for isolation. In this study, 2DMS electron capture dissociation (ECD) fragmentation of a polyoxazoline and polyacrylamide species was carried out, resulting in the analysis of byproducts and individual polymer species without the use of chromatographic techniques. This study shows that 2DMS ECD is a powerful tool for the analysis of polyacrylamide and polyoxazoline species and offers a new dimension in the characterization of polymers. |
| Databáze: | OpenAIRE |
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