Sexual selection does not increase the rate of compensatory adaptation to a mutation influencing a secondary sexual trait inDrosophila melanogaster
| Autor: | Ian Dworkin, Christopher H. Chandler, Anna E. Mammel |
|---|---|
| Přispěvatelé: | Biology |
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
sex combs distal QH426-470 Biology 010603 evolutionary biology 01 natural sciences 03 medical and health sciences Genetic variation Genetics sexual selection Molecular Biology Genetics (clinical) 030304 developmental biology sex comb scd1 0303 health sciences Experimental evolution Natural selection compensatory evolution natural selection drosophila Penetrance deleterious mutation Mate choice Sexual selection Mutation (genetic algorithm) Adaptation |
| Zdroj: | G3: Genes, Genomes, Genetics, Vol 10, Iss 5, Pp 1541-1551 (2020) |
| DOI: | 10.1101/686741 |
| Popis: | Theoretical work predicts that sexual selection can enhance natural selection, increasing the rate of adaptation to new environments and helping purge harmful mutations. While some experiments support these predictions, remarkably little work has addressed the role of sexual selection on compensatory adaptation—populations’ ability to compensate for the costs of deleterious alleles that are already present. We tested whether sexual selection, as well as the degree of standing genetic variation, affect the rate of compensatory evolution via phenotypic suppression in experimental populations ofDrosophila melanogaster. These populations were fixed for a spontaneous mutation causing mild abnormalities in the male sex comb, a structure important for mating success. We fine-mapped this mutation to an ∼85 kb region on the X chromosome containing three candidate genes, showed that the mutation is deleterious, and that its phenotypic expression and penetrance vary by genetic background. We then performed experimental evolution, including a treatment where opportunity for mate choice was limited by experimentally enforced monogamy. Although evolved populations did show some phenotypic suppression of the morphological abnormalities in the sex comb, the amount of suppression did not depend on the opportunity for sexual selection. Sexual selection, therefore, may not always enhance natural selection; instead, the interaction between these two forces may depend on additional factors. |
| Databáze: | OpenAIRE |
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