Formation and Out‐of‐Equilibrium, High/Low State Switching of a Nitroaldol Dynamer in Neutral Aqueous Media
| Autor: | Ulla Elofsson, Oleksandr Kravchenko, Olof Ramström, Zoltán Szabó, Mingdi Yan, Antanas Karalius, Yang Zhang |
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| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
Physics::Biological Physics Aqueous medium 010405 organic chemistry Formaldehyde Dynamic covalent chemistry General Chemistry Polymer 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences Stimulus response Condensed Matter::Soft Condensed Matter chemistry.chemical_compound chemistry Chemical engineering State switching Physics::Chemical Physics |
| Zdroj: | Angewandte Chemie International Edition. 59:3434-3438 |
| ISSN: | 1521-3773 1433-7851 |
| DOI: | 10.1002/anie.201911706 |
| Popis: | The nitroaldol reaction is demonstrated as an efficient dynamic covalent reaction in phosphate buffers at neutral pH. Rapid equilibration was recorded with pyridine-based aldehydes, and dynamic oligomerization could be achieved, leading to nitroaldol dynamers of up to 17 repeating units. The dynamers were applied in a coherent stimuli-responsive molecular system in which larger dynamers transiently existed out-of-equilibrium in a neutral aqueous system rich in formaldehyde, controlled by nitromethane. |
| Databáze: | OpenAIRE |
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