Efficacy of aSalmonellaSiderophore Receptor Protein Vaccine on Fecal Shedding and Lymph Node Carriage ofSalmonellain Commercial Feedlot Cattle
| Autor: | Natalia Cernicchiaro, Tiruvoor G. Nagaraja, Thomas S. Edrington, Samuel E. Ives, David G. Renter |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Serotype Veterinary medicine Salmonella Salmonella Vaccines 040301 veterinary sciences 030106 microbiology Colony Count Microbial Cattle Diseases Porins Receptors Cell Surface Biology medicine.disease_cause Applied Microbiology and Biotechnology Microbiology 0403 veterinary science Feces Random Allocation 03 medical and health sciences Immunity medicine Animals Bacterial Shedding Salmonella Infections Animal 04 agricultural and veterinary sciences Salmonella vaccine Vaccine efficacy Texas Vaccination Carriage Animals Domestic Cattle Animal Science and Zoology Lymph Nodes Bacterial Outer Membrane Proteins Food Science |
| Zdroj: | Foodborne Pathogens and Disease. 13:517-525 |
| ISSN: | 1556-7125 1535-3141 |
| Popis: | The efficacy of a Salmonella vaccine for reducing fecal shedding of Salmonella during the finishing period and lymph node (LN) carriage at harvest was investigated in commercial feedlot cattle. The study was designed as a pen-level randomized complete block with two treatment groups, a Salmonella Newport siderophore receptor and porin proteins-based vaccine (VAC) and a nonvaccinated control (CON). Cattle were randomly allocated into 24 pens within 12 blocks based on the time of allocation. Twenty to 25 fecal pats were collected from each of the study pen floors once a month from June to August 2013. During harvest, a minimum of 25 sub-iliac LN were collected from carcasses within each study pen. Fecal and pulverized LN samples were cultured for Salmonella quantification and detection. Mixed models were used to analyze the effect of vaccination on fecal shedding and LN carriage of Salmonella. Montevideo and Anatum were the predominant Salmonella serotypes among fecal samples and LNs; no Newport isolates were recovered. Vaccination was not significantly associated (p = 0.57) with the prevalence of Salmonella in feces over time; the mean within-pen prevalence was 62.3% and 66.0% among VAC and CON, respectively. Sampling month was significantly associated (p |
| Databáze: | OpenAIRE |
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