Intradiscal vacuum phenomenon and spinal degeneration: a cross-sectional analysis of 219 subjects
| Autor: | Maftun Zarbizada, Alper Akkaş, Murat Şakir Ekşi, Doğu Küçüksüleymanoğlu, Ömer Orhun, Emel Ece Özcan-Ekşi, M. Necmettin Pamir, Havva Nur Arslan, Edward C. Benzel |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Vacuum Cross-sectional study Intervertebral Disc Degeneration Malignancy Lumbar Medicine Humans Intervertebral Disc Lumbar Vertebrae medicine.diagnostic_test business.industry Magnetic resonance imaging Modic changes Intervertebral disc General Medicine medicine.disease Low back pain Magnetic Resonance Imaging medicine.anatomical_structure Cross-Sectional Studies Concomitant Radiology medicine.symptom business Low Back Pain |
| Zdroj: | Current medical research and opinion. 38(2) |
| ISSN: | 1473-4877 |
| Popis: | Introduction Intradiscal vacuum phenomenon (IVP) is the collection of gas within the intervertebral discs. It has been reported with various spinal disorders. The exact role of IVP in spinal degeneration leading to low back pain (LBP) is unclear. We aimed to obtain the prevalence of IVP in patients with LBP. Our second aim was to understand whether IVP was associated with intervertebral disc degeneration (IVDD), Modic changes, and subchondral sclerosis (SS). Methods A total of 12.450 consecutive patients with chronic LBP were evaluated in terms of having abdominal computed tomography (CT) scan concomitant with lumbar spine magnetic resonance imaging (MRI) using radiological database of three spine centers. We excluded the patients with a history of malignancy, metabolic disease, spinal infection, traumatic or osteoporotic spine fracture, and spine surgery. All lumbar levels were evaluated in terms of IVDD and Modic changes on MRI, while they were evaluated in terms of IVP and SS on CT scans. Results We included 219 patients. Severe IVDD, Modic changes, IVP, and SS were seen in 53.9% (n: 118), 38.8% (n: 85), 26.5% (n: 58), and 16% (n: 35) of the patients, respectively. Intradiscal vacuum phenomenon was closely associated with severe IVDD (OR: 8.204), Modic changes (OR: 3.547) and SS (OR: 4.231). Discussion Intradiscal vacuum phenomenon was closely associated with severe IVDD, Modic changes, and SS. Further prospective clinical and laboratory studies are necessary to better delineate the pathogenesis of IVP. |
| Databáze: | OpenAIRE |
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