Association of Cytokine Production with Hormone Level and Sensory Responses during the Formation of Psychoactive Drug Addiction in Men
| Autor: | D. N. Savochkina, T. I. Nevidimova, Nikolay A. Bokhan, E. I. Batukhtina, T. P. Vetlugina, O. A. Lobacheva, Nikitina Vb |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Nociception medicine.medical_specialty Adolescent Substance-Related Disorders media_common.quotation_subject Physiology General Biochemistry Genetics and Molecular Biology Proinflammatory cytokine Young Adult chemistry.chemical_compound Internal medicine medicine Humans Young adult media_common Psychotropic Drugs business.industry Addiction Psychoactive drug Case-control study Androstenone General Medicine Hormones Smell Endocrinology chemistry Case-Control Studies Cytokines Inflammation Mediators business Hormone medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 159:768-771 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | We performed immunophysiological examination of 144 men aged 17-25 years, patients with psychoactive substance dependence, episodic psychoactive drug users, and conditionally healthy individuals. Associations of proinflammatory cytokine production with age, sex, hormone levels, and olfactory and nociceptive indices were revealed in cases of psychoactive drug use and formation of addiction. Predictive models based on the use of androstenone aversion, pressure algometry testing, and immunological parameters were proposed. |
| Databáze: | OpenAIRE |
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