A COMPARATIVE STUDY OF THE SULFATION FACTOR AND IMMUNODETECTABLE GROWTH HORMONE IN SERUM
| Autor: | Hans Yde |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
medicine.medical_specialty
Chemistry Endocrinology Diabetes and Metabolism Radioimmunoassay General Medicine Growth hormone Blood Endocrinology Growth Hormone Sulfation Factor Internal medicine Acromegaly Diabetes Mellitus Methods medicine Humans Biological Assay Diabetic Angiopathies Sulfur Hypophysectomy |
| Zdroj: | Acta Endocrinologica. 62:49-55 |
| ISSN: | 1479-683X 0804-4643 |
| Popis: | Using a modified sulfation factor (SF) method involving the use of nonhypophysectomized animals as cartilage donors, a fall in serum SF was found after hypophysectomy in diabetic patients. At the same time immuno-reactive growth hormone (IRGH) disappeared from the serum of these patients. In the fasting serum of 52 newly diagnosed untreated diabetics, 22 patients with severe diabetic angiopathy and 10 non-diabetics, no correlation was observed between the serum SF and IRGH. This discrepancy may be due to the non-specificity of SF or to a time lag between the secretion of growth hormone and the production of the growth hormone dependent sulfation factor. |
| Databáze: | OpenAIRE |
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