Sinonasal Undifferentiated Carcinoma with Failed Response to Induction Chemotherapy

Autor: Michael R. Papazian, Alex J. Gordon, Michael Chow, Aneek Patel, Donato Pacione, Seth Lieberman, Babak Givi
Rok vydání: 2022
Předmět:
Zdroj: Journal of Neurological Surgery Reports. 83:e83-e86
ISSN: 2193-6366
2193-6358
Popis: Sinonasal undifferentiated carcinoma (SNUC) is a rapidly growing malignancy with a propensity for extensive local invasion. Multimodal therapy, including surgery, radiotherapy, and chemotherapy, is the standard approach to treatment, but the optimal sequence and combination of these modalities are uncertain. Induction chemotherapy is being increasingly utilized based on recent reports that show better outcomes for patients who respond to chemotherapy and the ability to determine further course of treatment. We present a unique case of a patient with locally advanced SNUC that did not respond to induction chemotherapy and a review of the available literature relating to the management of this rare malignancy.
Databáze: OpenAIRE