Sinonasal Undifferentiated Carcinoma with Failed Response to Induction Chemotherapy
Autor: | Michael R. Papazian, Alex J. Gordon, Michael Chow, Aneek Patel, Donato Pacione, Seth Lieberman, Babak Givi |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Journal of Neurological Surgery Reports. 83:e83-e86 |
ISSN: | 2193-6366 2193-6358 |
Popis: | Sinonasal undifferentiated carcinoma (SNUC) is a rapidly growing malignancy with a propensity for extensive local invasion. Multimodal therapy, including surgery, radiotherapy, and chemotherapy, is the standard approach to treatment, but the optimal sequence and combination of these modalities are uncertain. Induction chemotherapy is being increasingly utilized based on recent reports that show better outcomes for patients who respond to chemotherapy and the ability to determine further course of treatment. We present a unique case of a patient with locally advanced SNUC that did not respond to induction chemotherapy and a review of the available literature relating to the management of this rare malignancy. |
Databáze: | OpenAIRE |
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