Effects of menthol on the triggering of the swallowing reflex in elderly patients with dysphagia

Autor: Takae Ebihara, Hiroyuki Arai, Mutsuo Yamaya, Tatsuma Okazaki, Aya Watando, Satoru Ebihara, Takashi Ohrui, Masanori Asada
Rok vydání: 2006
Předmět:
Zdroj: British Journal of Clinical Pharmacology. 62:369-371
ISSN: 1365-2125
0306-5251
DOI: 10.1111/j.1365-2125.2006.02666.x
Popis: Aims To investigate the effect of menthol on swallowing reflex sensitivity in elderly patients with dysphagia. Methods and results The swallowing reflex sensitivity of institutionalized elderly patients was evaluated as a latent time of swallowing reflex (LTSR), induced by the injection of 1 ml solution into the pharynx. LTSR was significantly shortened in a concentration-dependent manner, from 13.8 s [95% confidence interval (CI) 11.1, 16.5] by distilled water to 9.4 s (95% CI 7.1. 11.8) by 10−2m menthol. Conclusion Using menthol with elderly patients with dysphagia may improve the sensitivity of their swallowing reflex, resulting in prevention of aspiration pneumonia.
Databáze: OpenAIRE