Exosomes in the pathogenesis and treatment of ocular diseases
| Autor: | Zhihan Zhang, Min Fu, Jing Zhou, Xiaotian Liang, Meijun Meng, Ya Gao, Guoguo Yi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Eye Diseases
business.industry Immune regulation Disease Management Mesenchymal Stem Cells Cell Communication medicine.disease Exosomes Viral infection Sensory Systems Microvesicles Metastasis Pathogenesis Cellular and Molecular Neuroscience Ophthalmology Clinical diagnosis Cancer research Medicine Humans Stem cell business |
| Zdroj: | Experimental eye research. 209 |
| ISSN: | 1096-0007 |
| Popis: | Exosomes have diverse functions and rich content and are involved in intercellular communication, immune regulation, viral infection, tissue regeneration, and the occurrence, development and metastasis of tumours. Notably, various stem cell-derived exosomes are expected to become new therapeutic approaches for inflammatory diseases and tumours and have good clinical application prospects. However, few studies have examined exosomes in ophthalmic diseases. Therefore, based on the functions of exosomes, this paper summarizes progress in the possible use of exosomes as treatment for specific ophthalmic diseases, aiming to determine the pathogenesis of exosomes to achieve more effective clinical diagnosis and treatment of these diseases. |
| Databáze: | OpenAIRE |
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