Exacerbation of Chronic Obstructive Pulmonary Disease
| Autor: | Xianghui Zhou, Xincan Zhou, Qingling Li |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Exacerbation Biophysics Review Disease Biochemistry Pulmonary Disease Chronic Obstructive Quality of life (healthcare) Health care medicine COPD Humans RNA Viruses Microbiome Intensive care medicine Innate immunity Inflammation Original Paper Bacteria business.industry DNA Viruses Cell Biology General Medicine medicine.disease Immunity Innate Pathophysiology Virus respiratory tract diseases Immunology Disease Progression Quality of Life business Airway |
| Zdroj: | Cell Biochemistry and Biophysics |
| ISSN: | 1559-0283 1085-9195 |
| DOI: | 10.1007/s12013-015-0605-9 |
| Popis: | Chronic obstructive pulmonary disease (COPD) is a disease with high prevalence and substantial associated economical burden. A significant determinant of quality of life, long-term survival, and health care costs is an acute exacerbation of COPD. Acute exacerbations are provoked by respiratory viruses, altered airway microbiome, and environmental factors. The current treatment options are limited. In order to develop specific therapeutic measures, it is important to understand how acute exacerbations evolve. This review focuses on pathophysiology of stable and exacerbated COPD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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