Efficacy of Transnasal Endoscopic Fine‐Needle Aspiration Biopsy in Diagnosing Submucosal Nasopharyngeal Carcinoma
Autor: | Jin-Jie Yan, Hao-Jun Xie, Yue-Feng Wen, Jin-Hao Yang, Xiao-Yun Li, Sai-Lan Liu, Qing-Nan Tang, Shan-Shan Guo, Jibin Li, Guo-Ping Ou, Zi-Jian Lu, Xue-Song Sun, Hai-Qiang Mai, Lin-Quan Tang, Dong-Xiang Wen, Li-Ting Liu, Qiu-Yan Chen |
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Rok vydání: | 2021 |
Předmět: |
Adult
Image-Guided Biopsy Male medicine.medical_specialty Diagnostic methods Biopsy Fine-Needle Young Adult 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Nasopharynx Aspiration biopsy Biopsy Mucositis medicine Humans Aged Aged 80 and over Nasopharyngeal Carcinoma medicine.diagnostic_test Receiver operating characteristic business.industry Endoscopy Nasopharyngeal Neoplasms Middle Aged medicine.disease Predictive value Nasal Mucosa Fine-needle aspiration ROC Curve Otorhinolaryngology Nasopharyngeal carcinoma 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology Radiology business |
Zdroj: | The Laryngoscope. 131:1798-1804 |
ISSN: | 1531-4995 0023-852X |
DOI: | 10.1002/lary.29433 |
Popis: | OBJECTIVES/HYPOTHESIS The routine practices of examining submucosal lesions are not suitable for deep lesions. Therefore, we evaluated the efficacy of non-real-time image-guided transnasal endoscopic fine-needle aspiration biopsy (FNAB) in diagnosing nasopharyngeal carcinoma (NPC) with submucosal lesions. STUDY DESIGN The effectiveness evaluation of diagnostic methods. METHODS Fifty suspected NPC patients who failed in conventional biopsies were enrolled in this study. The efficacy, maneuverability, and safety of FNAB in diagnosing these intractable cases were evaluated. RESULTS The definitive diagnostic results of these 50 patients were NPC (34/50, 68.0%), nasopharyngeal necrosis (1/50, 2.0%), nasopharyngeal mucositis (12/50, 24.0%), and other cancers (3/50, 6.0%), respectively. The results of the diagnostic efficacy of FNAB were sensitivity, 89.2%; specificity, 100.0%; positive predictive value, 100.0%; negative predictive value, 76.5%; and accuracy, 92.0%, respectively. The area under the receiver operating characteristic curves was 0.946 (95% confidence interval = 0.884-1.00, P |
Databáze: | OpenAIRE |
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