Seizure Semiology and Neuroimaging Findings in Patients with Midline Spikes
Autor: | Ahmad Beydoun, Diana Gomez-Hassan, Ekrem Kutluay, Erasmo A. Passaro |
---|---|
Rok vydání: | 2001 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Epilepsy Frontal Lobe Neurological disorder Electroencephalography Audiology Epilepsy Neuroimaging Convulsion medicine Humans Child medicine.diagnostic_test Seizure types Age Factors Brain Infant medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Neurology Frontal lobe Child Preschool Scalp Anesthesia Epilepsy Generalized Female Epilepsies Partial Neurology (clinical) medicine.symptom Tomography X-Ray Computed Psychology |
Zdroj: | Epilepsia. 42:1563-1568 |
ISSN: | 1528-1167 0013-9580 |
Popis: | Summary: Purpose: Midline epileptiform discharges are rare compared with discharges at other scalp locations. Neuroimaging results and semiologic seizure characteristics of patients with midline spikes are not adequately described. The aim of this study was to describe the neuroimaging findings and detailed seizure semiologies in patients with midline spikes. Methods: We reviewed the EEG database of the University of Michigan Medical Center and identified 35 patients with midline spikes. Information about seizure types and neuroimaging results was obtained from a review of medical records. The seizures were classified according to the International League Against Epilepsy (ILAE) criteria and semiologic classification. Results: Twenty-nine (83%) patients had a history of seizures. Complex partial seizures and simple partial seizures were the most common seizure types, experienced by 66% of patients. The age at seizure onset was within the first 10 years in 90% of patients. According to the semiologic seizure classification, automotor seizures and tonic seizures were the most common seizure types. Neuroimaging studies were abnormal in 45% of patients. When focal abnormalities were detected, they were lateralized to one of the frontal lobes in all cases. Conclusions: Our results indicate that in the majority of patients, midline spikes represent focal epileptiform activity rather than fragments of generalized discharges, and are most commonly associated with seizures of partial onset. Automotor seizures and tonic seizures are the most common semiologies. Focal radiologic abnormalities tend to be lateralized to one of the frontal lobes. Key Words: Midline spikes—Semiologic seizure classification—Neuroimaging—Frontal lobe—Tonic seizures. |
Databáze: | OpenAIRE |
Externí odkaz: |