Respiratory modulation of cardiac vagal tone in Lyme disease
| Autor: | Michele C. Kingston, Basant K. Puri, Mussadiq Shah, Jean A. Monro, Peter O.O. Julu |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Pathology business.industry digestive oral and skin physiology Observational Study Diaphragmatic breathing Respiratory modulation bacterial infections and mycoses medicine.disease RESTING HEART RATE Vagus nerve Lyme disease Blood pressure Internal medicine medicine Cardiology Brainstem Cardiac vagal tone Cardiology and Cardiovascular Medicine business |
| Zdroj: | World Journal of Cardiology. 6:502 |
| ISSN: | 1949-8462 |
| DOI: | 10.4330/wjc.v6.i6.502 |
| Popis: | AIM: To conduct the first systematic test of the hypothesis that modulation of cardiac vagal tone is impaired in Lyme disease. METHODS: The response of cardiac vagal tone to respiratory modulation was measured in 18 serologically positive Lyme disease patients and in 18 controls. RESULTS: The two groups were matched in respect of age, sex, body mass, mean arterial blood pressure, mean resting heart rate and mean resting cardiac vagal tone. The mean maximum cardiac vagal tone during deep breathing in the Lyme disease patients [11.2 (standard error 1.3)] was lower than in the matched controls [16.5 (standard error 1.7); P = 0.02]. CONCLUSION: Respiratory modulation of cardiac vagal tone is impaired in Lyme disease, which suggests that Lyme disease may directly affect the vagus nerve or the brainstem. |
| Databáze: | OpenAIRE |
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