Acute Pancreatitis: A Rare but Serious Complication for Living Liver Donors; Risk Factors and Outcomes
| Autor: | Serdar Karakas, Metin Kement, Bora Barut, Sezai Yilmaz, Adil Baskiran, Cemalettin Koc, Oguzhan Ozsay |
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| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Postoperative Complications Blood loss Risk Factors Living Donors Hepatectomy Humans Medicine Transplantation business.industry Incidence (epidemiology) medicine.disease Liver Transplantation Surgery Treatment Outcome Liver Pancreatitis Acute Disease Liver donors Acute pancreatitis business Complication Body mass index |
| Zdroj: | Experimental and Clinical Transplantation. 20:413-419 |
| ISSN: | 2146-8427 1304-0855 |
| Popis: | Objectives The purposes of this study were to determine the incidence of acute pancreatitis after living donor hepatectomy and to investigate potential risk factors and outcomes. Materials and methods Clinical data of all donors who underwent donor hepatectomy between January 2015 and December 2016 in our liver transplant institute were reviewed. Donor data were obtained from a prospectively maintained database. The donors were divided into 2 groups according to whether they developed postoperative pancreatitis. The following data were compared between the 2 groups: demo-graphic information (age, sex), body mass index, type of hepatectomy (right, left, or left lateral), intraoperative cholangiographic findings, operative time, blood loss, graft data (graft weight, remnant liver ratio), duration of postoperative hospital stay, and postoperative morbidity and mortality (if any). Pancreatitis severity and treatment outcomes were also examined in patients with postoperative pancreatitis. Results Our study included 348 donors who underwent donor hepatectomy for living-donor liver transplant. Postoperative pancreatitis developed in 6 donors (1.7%). We found no statistical differences between patients with and without postoperative pancreatitis in terms of demographic and intra-operative findings. Neither loco-regional nor systemic complications of pancreatitis developed in any of the patients. Therefore, all were classified as having mild pancreatitis according to revised Atlanta classification. The mean APACHE II score was 5.2 ± 1.2 points (range, 4-7 points). All patients with postoperative pancreatitis received conservative-supportive treatment. Conclusions Although postoperative pancreatitis is a rarely reported complication in living liver donors, it should always be considered, especially in patients who unpredictably deteriorate in the postoperative period. Proper recognition and timely treatment can help avoid serious consequences. |
| Databáze: | OpenAIRE |
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