Everolimus-eluting bioresorbable vascular scaffolds for treatment of complex chronic total occlusions

Autor: Fam, Jiang Ming, Ojeda, Soledad, Garbo, Roberto, Latib, Azeem, La Manna, Alessio, Vaquerizo, Beatriz, Boukhris, Marouane, Vlachojannis, Georgios J., Van Geuns, Robert jan, Ezhumalai, Babu, Kawamoto, Hiroyoshi, Van Der Sijde, Jors, Felix, Cordula, Pan, Manuel, Serdoz, Roberta, Boccuzzi, Giacomo Giovanni, De Paolis, Marcella, Sardella, Gennaro, Mancone, Massimo, Tamburino, Corrado, Smits, Pieter C., Di Mario, Carlo, Seth, Ashok, Serra, Antonio, Serruys, Patrick, Galassi, Alfredo R., Zijlstra, Felix, Van Mieghem, Nicolas M., Diletti, Roberto, Thiele, Holger, COLOMBO, ANTONIO
Přispěvatelé: Fam, Jiang Ming, Ojeda, Soledad, Garbo, Roberto, Latib, Azeem, La Manna, Alessio, Vaquerizo, Beatriz, Boukhris, Marouane, Vlachojannis, Georgios J., Van Geuns, Robert jan, Ezhumalai, Babu, Kawamoto, Hiroyoshi, Van Der Sijde, Jor, Felix, Cordula, Pan, Manuel, Serdoz, Roberta, Boccuzzi, Giacomo Giovanni, De Paolis, Marcella, Sardella, Gennaro, Mancone, Massimo, Tamburino, Corrado, Smits, Pieter C., Di Mario, Carlo, Seth, Ashok, Serra, Antonio, Colombo, Antonio, Serruys, Patrick, Galassi, Alfredo R., Zijlstra, Felix, Van Mieghem, Nicolas M., Diletti, Roberto, Thiele, Holger, Cardiology
Rok vydání: 2017
Předmět:
Target lesion
Adult
Male
Bioresorbable scaffold
stable angina
Chronic coronary total occlusion
Stable angina
Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]
Coronary Artery Disease
030204 cardiovascular system & hematology
Balloon
bioresorbable
Lesion
03 medical and health sciences
0302 clinical medicine
Text mining
Percutaneous Coronary Intervention
Absorbable Implants
medicine
Humans
030212 general & internal medicine
Myocardial infarction
Everolimus
Registries
chronic total occlusion
Aged
scaffolds
Tissue Scaffolds
bioresorbable scaffolds
business.industry
Drug-Eluting Stents
chronic coronary total occlusion
Middle Aged
medicine.disease
Thrombosis
Treatment Outcome
Coronary Occlusion
Chronic Disease
Female
Artery diseases
medicine.symptom
business
Nuclear medicine
Cardiology and Cardiovascular Medicine
medicine.drug
Zdroj: Eurointervention, 13, 3, pp. 355-363
Eurointervention, 13, 355-363
EuroIntervention, 13(3), 355-363. EuroPCR
EuroIntervention
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
ISSN: 1774-024X
Popis: Item does not contain fulltext AIMS: Bioresorbable vascular scaffolds (BVS) represent a novel therapeutic option for the treatment of coronary artery diseases. The objective of this study was to evaluate the feasibility of BVS implantation in complex chronic total occlusions (CTO). METHODS AND RESULTS: The present report is a multicentre registry evaluating results after BVS deployment in challenging CTO lesions, defined as J-CTO score >/=2 (difficult or very difficult). A total of 105 patients were included in the present analysis. The mean J-CTO score was 2.61 (difficult 52.4%, very difficult 47.6%). Device success and procedural success rates were 98.1% and 97.1%, respectively. The retrograde approach was used in 25.7% of cases. After wire crossing, predilatation was performed in all cases with a mean predilatation balloon diameter of 2.73+/-0.43 mm. The mean scaffold length was 59.75+/-25.85 mm, with post-dilatation performed in 89.5% of the cases and a mean post-dilatation balloon diameter of 3.35+/-0.44 mm. Post-PCI minimal lumen diameter was 2.50+/-0.51 mm and percentage diameter stenosis 14.53+/-10.31%. At six-month follow-up, a total of three events were reported: one periprocedural myocardial infarction, one late scaffold thrombosis and one additional target lesion revascularisation. CONCLUSIONS: The present report suggests the feasibility of BVS implantation in complex CTO lesions, given adequate lesion preparation and post-dilatation, with good acute angiographic results and midterm clinical outcomes.
Databáze: OpenAIRE