Does chronic kidney disease affect the mortality rate in patients undergoing spine surgery?
| Autor: | Ravi S. Bains, Elizabeth W. Paxton, Lance Mitsunaga, Kamran Majid, Yuexin Chen, Jessica Harris, Mayur Kardile |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Renal function Logistic regression Cohort Studies 03 medical and health sciences Young Adult 0302 clinical medicine Physiology (medical) Internal medicine medicine Risk of mortality Humans 030212 general & internal medicine Stage (cooking) Renal Insufficiency Chronic Aged Retrospective Studies Aged 80 and over business.industry Mortality rate Confounding General Medicine Middle Aged medicine.disease Surgery Spinal Fusion Neurology Cohort Female Spinal Diseases Neurology (clinical) business 030217 neurology & neurosurgery Kidney disease |
| Zdroj: | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 43 |
| ISSN: | 1532-2653 |
| Popis: | The number of patients with chronic kidney disease (CKD) and their life expectancy has been increasing. With time number of patients undergoing spine surgery has also been on a rise. This study we did a retrospective review of registry data to investigate the mortality rate of chronic kidney disease patients following spine surgery using a large, multi-center spine registry. 12,276 consecutive spine-fusion patients from January 2009 to December 2012 were included and mortality rates in patients with CKD compared to those with normal kidney function following spine surgery. Logistic regression was usedto evaluate risk of mortality following spine surgery. The average age of the cohort was 59 (SD=13.4). 53% were female. Patients who had stage 3, 4 or 5 CKD were older than non-CKD patients (mean=71,SD=9.2 vs. 59, SD=13.3). After adjusting for confounding variables, patients with stage 3 or 4 CKD had higher mortality rates than patients with normal kidney function (OR 1.78, 95% CI 1.3-2.45) Hemodialysis-dependent patients (stage 5 CKD) had even higher rates of mortality compared to patients with normal function (OR 4.18, 95% CI1.87-9.34). our findings suggest that spine surgery is associated with significantly higher mortality rates in patients with CKD compared to patients with normal kidney function. Understanding the additional morbidity and mortality of spine surgery in this medically complicated group of patients is imperative for accurate preoperative risk assessment. |
| Databáze: | OpenAIRE |
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