Haemorrhage associated with large abdominal aortic aneurysms
Autor: | A. K. Ah‐See, A. A. Dawson, P. W. Buckler, Bruce Bennett, Nuala A. Booth |
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Rok vydání: | 2008 |
Předmět: |
Male
medicine.medical_specialty Plasmin medicine.medical_treatment Hemorrhage Plasminogen Activators Postoperative Complications Internal medicine Fibrinolysis medicine Humans Platelet Aorta Abdominal Fibrinolysin Aged Aortic graft business.industry Hematology Aortic Aneurysm Surgery Coagulation Minor surgery cardiovascular system Cardiology business medicine.drug |
Zdroj: | Clinical & Laboratory Haematology. 6:123-131 |
ISSN: | 0141-9854 |
Popis: | Summary. Two patients are described who each had a major haemorrhage after minor surgery and who additionally had large abdominal aortic aneurysms. Neither had depletion of platelets or coagulation factors sufficient to account for bleeding. Both had grossly enhanced fibrinolytic activity with evidence of plasmin generation in the circulation. In one patient insertion of an aortic graft was rapidly followed by resolution of the fibrinolytic abnormalities. Overactive fibrinolysis, rather than coagulation factor consumption may account for some of the bleeding syndromes complicating abdominal aortic aneurysms. |
Databáze: | OpenAIRE |
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