Perioperative Risks of Dietary and Herbal Supplements
| Autor: | Elad Schiff, Samuel Attias, Ibrahim Matter, Eran Ben-Arye, Ilana Levy, Mostafa Somri, Lee H. Goldstein |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Cross-sectional study Herb-Drug Interactions MEDLINE Alternative medicine Hemorrhage 030204 cardiovascular system & hematology Logistic regression 03 medical and health sciences 0302 clinical medicine Fibrinolytic Agents medicine Humans Hypnotics and Sedatives Prospective Studies 030212 general & internal medicine Intraoperative Complications Prospective cohort study Anesthetics business.industry Anticoagulants Perioperative Middle Aged Vascular surgery Surgery Cross-Sectional Studies Dietary Supplements Emergency medicine Female business Platelet Aggregation Inhibitors Phytotherapy Abdominal surgery |
| Zdroj: | World Journal of Surgery. 41:927-934 |
| ISSN: | 1432-2323 0364-2313 |
| Popis: | Patients undergoing surgery often use Dietary and Herbal Supplements (DHS). We explored the risk of DHS–drug interactions in the perioperative setting. In this cross-sectional prospective study, participants hospitalized for surgery completed a questionnaire regarding DHS use. We used pharmacological databases to assess DHS–drug interactions. We then applied univariate and multivariate logistic regression analyses to characterize patients at risk for DHS–drug interactions. Of 526 interviewees, 230 (44%) patients reported DHS use, with 16.5% reporting using DHS that could potentially interact with anesthesia. Twenty-four (10%) patients used DHS that could potentially interact with antithrombotic drugs taken perioperatively. The medical files of three patients included reports of intraoperative bleeding. The patient files of only 11% of DHS users documented DHS use. DHS use poses a significant health risk due to potential interactions. Guidelines should emphasize perioperative management of DHS use. |
| Databáze: | OpenAIRE |
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