Primary adenocarcinoma of the vagina successfully treated with neoadjuvant chemotherapy consisting of paclitaxel and carboplatin
Autor: | Shuji Takemoto, Naoki Fujiyoshi, Toshiharu Kamura, Kimio Ushijima, Kazumi Nakaso |
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Rok vydání: | 2009 |
Předmět: |
medicine.medical_specialty
Vaginal Neoplasms Paclitaxel medicine.medical_treatment Vaginal neoplasm Adenocarcinoma Carboplatin chemistry.chemical_compound medicine Humans Vaginal bleeding Neoadjuvant therapy Aged Chemotherapy business.industry Obstetrics and Gynecology medicine.disease Magnetic Resonance Imaging Neoadjuvant Therapy Surgery Radiation therapy medicine.anatomical_structure chemistry Vagina Female medicine.symptom business |
Zdroj: | Journal of Obstetrics and Gynaecology Research. 35:579-583 |
ISSN: | 1447-0756 1341-8076 |
DOI: | 10.1111/j.1447-0756.2008.00979.x |
Popis: | Primary vaginal adenocarcinoma unassociated with antenatal diethylstilbestrol (DES) exposure is extremely rare. The strategy for treating this disease has not yet been established due to its rarity and, therefore, the prognosis remains poor. A 69-year-old woman presented with vaginal bleeding but no history of antenatal DES exposure. She had a solid tumor in the recto-vaginal space, diagnosed as FIGO stage III vaginal adenocarcinoma. After neoadjuvant chemotherapy consisting of paclitaxel and carboplatin, the tumor became undetectable. Thereafter, radiotherapy was applied to the pelvis and vagina in order to reinforce the state of remission. The patient remains free from recurrence 1 year after discharge. The present case was successfully treated with chemotherapy and radiotherapy, suggesting that chemotherapy may be an option for the treatment of this type of tumor. |
Databáze: | OpenAIRE |
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