A New One-Pot, Four-Component Synthesis of 1,2-Amino Alcohols: TiCl3/t-BuOOH-Mediated Radical Hydroxymethylation of Imines
| Autor: | Carlo Punta, Angelo Clerici, Ombretta Porta, Nadia Pastori, Alessandra Ghilardi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
chemistry.chemical_classification
Aldehydes Aqueous solution Free Radicals Molecular Structure Four component Butanols fungi Organic Chemistry food and beverages Hydroxylation Amino Alcohols Methylation Biochemistry Aldehyde humanities chemistry.chemical_compound chemistry Organic chemistry Amine gas treating Imines Methanol Thallium Physical and Theoretical Chemistry |
| Popis: | An amine, an aldehyde, and methanol can be readily assembled in one pot under very mild conditions through a free-radical multicomponent reaction by using an aqueous acidic TiCl3/t-BuOOH system to afford 1,2-amino alcohols in fair to excellent yields. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|