CTRP-1 levels are related to insulin resistance in pregnancy and gestational diabetes mellitus
| Autor: | Dagmar Bancher-Todesca, Jürgen Harreiter, Sabina Baumgartner-Parzer, Carola Deischinger, Alexandra Kautzky-Willer, Karoline Leitner |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Blood Glucose 0301 basic medicine medicine.medical_specialty Waist endocrine system diseases Reproductive disorders medicine.medical_treatment Population lcsh:Medicine 030209 endocrinology & metabolism Type 2 diabetes Article 03 medical and health sciences Endocrinology 0302 clinical medicine Insulin resistance Pregnancy Internal medicine Glucose Intolerance medicine Humans Insulin education lcsh:Science education.field_of_study Multidisciplinary business.industry Postpartum Period lcsh:R Proteins nutritional and metabolic diseases Glucose Tolerance Test Translational research medicine.disease Gestational diabetes Diabetes Gestational 030104 developmental biology Gestation Female lcsh:Q Insulin Resistance business Biomarkers |
| Zdroj: | Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020) Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | Recent studies have shown higher levels of CTRP-1 (C1QTNF-related protein) in patients with type 2 diabetes compared to controls. We aimed at investigating CTRP-1 in gestational diabetes mellitus (GDM). CTRP-1 levels were investigated in 167 women (93 with normal glucose tolerance (NGT), 74 GDM) of a high-risk population for GDM. GDM was further divided into GDM subtypes depending on a predominant insulin sensitivity issue (GDM-IR) or secretion deficit (GDM-IS). Glucose tolerance was assessed with indices [Matsuda index, Stumvoll first phase index, insulin-secretion-sensitivity-index 2 (ISSI-2), area-under-the-curve (AUC) insulin, AUC glucose] derived from an oral glucose tolerance test (oGTT) performed at |
| Databáze: | OpenAIRE |
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