The Thyroid Reserve in Patients with Breast Cancer
| Autor: | SHINTARO SAITO, RIKIYA ABE, TOSHIRO SAKURADA, KATSUMI YOSHIDA, MICHIO KIMURA, MAKIKO YAMAMOTO, KAZUO KAISE, NOBUKO KAISE, KAORU YOSHINAGA |
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| Rok vydání: | 1977 |
| Předmět: |
Adult
endocrine system medicine.medical_specialty endocrine system diseases Breast Neoplasms General Biochemistry Genetics and Molecular Biology Thyroiditis Serum thyroxine Breast cancer Hypothyroidism Internal medicine medicine Humans In patient Aged Triiodothyronine business.industry Thyroid Thyroiditis Autoimmune Primary hypothyroidism General Medicine Middle Aged medicine.disease Thyroxine Endocrinology medicine.anatomical_structure business hormones hormone substitutes and hormone antagonists |
| Zdroj: | The Tohoku Journal of Experimental Medicine. 122:229-235 |
| ISSN: | 1349-3329 0040-8727 |
| Popis: | Patients with breast cancer were studied with regard to changes in the levels of serum thyroxine (T4) and serum triidothyronine (T3) after intramuscular administration of TSH for three days to investigate the thyroid reserve in these patients. The changes were examined also in normal subjects, in patients with Hashimoto's thyroiditis and primary hypothyroidism. In primary hypothyroidism no increase was seen in serum T4 and T3 levels after TSH administration, and the thyroid reserve was considered to be absent. In Hashimoto's thyroiditis the serum T3 levels after TSH administration were the same as in normal subjects, but the serum T4 levels were significantly lower than normal. This suggests that in patients with Hashimoto's thyroiditis the thyroid reserve is decreased and is in a state of so-called low thyroid reserve. In patients with breast cancer, however, the levels of serum T4 and T3 showed no difference as compared with those in normal subjects after TSH administration, and this implies that the thyroid reserve is well maintained. |
| Databáze: | OpenAIRE |
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