Supplementary Figure 5 from The Nedd8-Activating Enzyme Inhibitor MLN4924 Thwarts Microenvironment-Driven NF-κB Activation and Induces Apoptosis in Chronic Lymphocytic Leukemia B Cells

Autor: Alexey V. Danilov, Alan Eastman, Jennifer R. Brown, Peter E. Kebbekus, Olga V. Danilova, Leigh Ann Humphries, J. Claire Godbersen
Rok vydání: 2023
Popis: PDF file - 59KB, BMS-345541 leads to Bim upregulation in CLL. CLL cells (N=3) were co-cultured with CD40L-expressing stroma for 24 hours, followed by incubation with 2 - 12 microM BMS-345541 or vehicle control for 24 h. Cells were lysed and subjected to immunoblotting. 1 out of 3 representative images is shown.
Databáze: OpenAIRE