Characterization of the chitin biosynthesis process as a compensatory mechanism in thefks1mutant ofSaccharomyces cerevisiae

Autor:	C Castro, María Henar Valdivieso, Jose Angel Trilla, Cesar Roncero, L. J. García-Rodriguez, Angeles Duran
Rok vydání:	2000
Předmět:	Saccharomyces cerevisiae Proteins Chitin synthase III activity Saccharomyces cerevisiae Mutant Biophysics Chitin macromolecular substances Biochemistry Fungal Proteins Echinocandins chemistry.chemical_compound Structural Biology Gene Expression Regulation Fungal Genetics Molecular Biology Gene Chitin Synthase biology ATP synthase Mechanism (biology) Membrane Proteins Cell Biology Chitin synthase biology.organism_classification Compensatory mechanism carbohydrates (lipids) Phenotype chemistry Glucosyltransferases Enzyme Induction biology.protein Carrier Proteins Cell Division Gene Deletion Intracellular
Zdroj:	FEBS Letters. 478:84-88
ISSN:	0014-5793
DOI:	10.1016/s0014-5793(00)01835-4
Popis:	Deletion of the 1,3-β-D-glucan synthase gene FKS1 in Saccharomyces cerevisiae induces a compensatory mechanism that is reflected in a significant increase in chitin synthase III (CSIII) activity, leading to high rates of chitin synthesis. Deregulation of CSIII activity is mainly due to the intracellular delocalization of Chs3p and Chs4p, the two main components of the CSIII active complex.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ce4fe30fd2be7ff963111a91d0574f https://doi.org/10.1016/s0014-5793(00)01835-4 Zobrazit plný text záznamu Plný text