The phosphoinositide‐3‐OH‐kinase‐related kinases of Arabidopsis thaliana

Autor: George W. Templeton, Greg B. G. Moorhead
Rok vydání: 2005
Předmět:
Zdroj: EMBO reports. 6:723-728
ISSN: 1469-3178
1469-221X
DOI: 10.1038/sj.embor.7400479
Popis: The phosphoinositide-3-OH-kinase-related kinases (PIKKs) are atypical protein kinases exclusive to eukaryotes. They mediate the cellular response to a range of stresses, including genome and RNA surveillance and availability of nutrients for growth. Orthologues of five out of the six PIKK family members are present in plant genomes. Recent studies in plant PIKKs have revealed features unique to, and in common with, other PIKKs. This review summarizes the basic knowledge of these proteins in mammals and yeast in comparison with what is known for Arabidopsis and other plants.
Databáze: OpenAIRE