Adjunctive pharmacologic use in carotid endarterectomy: a review
Autor: | Akihito Muto, Tormod S. Westvik, Reuben Rutland, Fabio A. Kudo, Alan Dardik, David Gortler, Stephen P. Maloney |
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Rok vydání: | 2006 |
Předmět: |
medicine.medical_specialty
medicine.medical_treatment Adrenergic beta-Antagonists Angiotensin-Converting Enzyme Inhibitors Carotid endarterectomy Patient care law.invention Surgical therapy Randomized controlled trial law Medicine Humans Radiology Nuclear Medicine and imaging Carotid Stenosis Anesthetics Local Aspirin Endarterectomy Carotid business.industry Anti-Inflammatory Agents Non-Steroidal Anticoagulants General Medicine Perioperative medicine.disease Surgery Stenosis Chemotherapy Adjuvant Hydroxymethylglutaryl-CoA Reductase Inhibitors Cardiology and Cardiovascular Medicine business medicine.drug |
Zdroj: | Vascular. 14(2) |
ISSN: | 1708-5381 |
Popis: | Although carotid endarterectomy (CEA) is now widely accepted as the surgical therapy for carotid stenosis, the role of and indications and evidence for many pharmacologic agents that are used adjunctively in the perioperative setting have not been conclusively established. Aspirin (acetylsalicylic acid) is the pharmaceutical agent that has been studied most extensively in conjunction with CEA; other than aspirin and dextran, the use of many agents before, during, and after CEA has not been standardized. Prospective randomized trials are still needed to demonstrate efficacy, predict outcome, and determine the optimal use of these medications in their adjunctive use during CEA to improve patient care and obtain optimal surgical outcomes. |
Databáze: | OpenAIRE |
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