Pilot evaluation of a vacuum-assisted biopsy instrument for percutaneous renal biopsy in dogs
| Autor: | Marina Manashirova, Hugo Ochoa-Acuña, Lynetta J. Freeman, Hylton R. Gelb, Barrak M. Pressler, Hock Gan Heng, Stephen D. Lenz |
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| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Percutaneous Future studies Vacuum Pilot Projects Dogs Renal capsule Biopsy medicine Animals Dog Diseases Small Animals Percutaneous Renal Biopsy Kidney medicine.diagnostic_test business.industry Biopsy Needle Ultrasonography Doppler medicine.disease medicine.anatomical_structure Treatment Outcome Vacuum-Assisted Biopsy Female Kidney Diseases Radiology business Kidney disease |
| Zdroj: | Journal of the American Animal Hospital Association. 47(6) |
| ISSN: | 1547-3317 |
| Popis: | Kidney biopsies in dogs are commonly obtained using automated spring-loaded biopsy instruments. Interpretation of biopsies from dogs with glomerular disease requires examination of at least 5–10 glomeruli, with at least two biopsies usually required for full evaluation. The purpose of this study was to compare quality and interpretability of renal biopsies obtained from healthy dogs with a large-gauge, vacuum-assisted biopsy instrument versus two biopsies obtained with a spring-loaded biopsy needle. Twenty dogs were randomized into two groups, and percutaneous, ultrasound-guided renal biopsies were evaluated using standard criteria. There were no significant differences in the number of biopsies that contained renal tissue, cortex, or medulla. Biopsies obtained with either instrument contained an adequate number of glomeruli and an equivalent number of arterioles and severity of tissue compression. Differences included easier penetration of the renal capsule and collection of sufficient tissue for interpretation with only one instrument pass when using the vacuum-assisted device (vs two passes required with the spring-loaded instrument). Before use in client-owned dogs, future studies should evaluate whether these differences are clinically relevant advantages in the diagnostic evaluation of dogs with kidney disease, and determine the prevalence and severity of complications when using this larger gauge device. |
| Databáze: | OpenAIRE |
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