Chiral HPLC resolution of neutral pesticides
| Autor: | Massimo Sinibaldi, Carolina Marra, Stéphane Viel, C. M. Polcaro, Antonio Berti, Luisa Mannina |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
chiral separation
Chromatography Resolution (mass spectrometry) Silica gel Elution Clinical Biochemistry metolachlor ethofumesate Pharmaceutical Science hplc pesticides Biochemistry High-performance liquid chromatography Analytical Chemistry nmr Chiral column chromatography chemistry.chemical_compound herbicides chemistry Proton NMR Enantiomer Metolachlor |
| Zdroj: | Journal of liquid chromatography & related technologies 27 (2004): 49–61. doi:10.1081/JLC-120027085 info:cnr-pdr/source/autori:Chiara M. Polcaro, Antonio Berti, Luisa Mannina, Carolina Marra, Massimo Sinibaldi, Stéphane Viel/titolo:Chiral HPLC Resolution of Neutral Pesticides/doi:10.1081%2FJLC-120027085/rivista:Journal of liquid chromatography & related technologies (Print)/anno:2004/pagina_da:49/pagina_a:61/intervallo_pagine:49–61/volume:27 |
| DOI: | 10.1081/JLC-120027085 |
| Popis: | The direct HPLC resolution of two synthetic neutral pesticides, Metolachlor and Ethofumesate, was studied on silica gel coated with cellulose tris‐(3,5‐dimethylphenylcarbamate) derivative (Chiracel OD‐H). The specific composition of the mobile phase has allowed the full separation of the four Metolachlor stereoisomers, which had not previously been resolved on other chiral stationary phases. The isomer elution sequence of both resolved pesticides was determined by 1H NMR and polarimetric analyses. The chromatographic system, coupled with mass‐spectrometric detection, was used to determine the isomeric ratio of Metolachlor stereoisomers after incubation in soil. |
| Databáze: | OpenAIRE |
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