On Biocompatibility and Stability of Transversal Intrafascicular Multichannel Electrodes—TIME
| Autor: | Thomas Stieglitz, Paul Čvančara, Victor Lopezalvarez, Thomas Guiho, Xavier Navarro, Tim Boretius, David Guiraud |
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| Přispěvatelé: | Department of Microsystems Engineering [Freiburg] (IMTEK), University of Freiburg [Freiburg], Control of Artificial Movement and Intuitive Neuroprosthesis (CAMIN), Laboratoire d'Informatique de Robotique et de Microélectronique de Montpellier (LIRMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Universitat Autònoma de Barcelona (UAB), European Project: 602547,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-1,EPIONE(2013), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Inria Sophia Antipolis - Méditerranée (CRISAM) |
| Rok vydání: | 2016 |
| Předmět: |
Materials science
Biocompatibility Electrode Biocompatibilité 02 engineering and technology engineering.material Phantom limb pain Iridium oxide 021001 nanoscience & nanotechnology 3. Good health [SPI]Engineering Sciences [physics] 03 medical and health sciences 0302 clinical medicine Coating engineering Artificial hand [SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics Upper limb amputation 0210 nano-technology Ulnar nerve 030217 neurology & neurosurgery Biomedical engineering |
| Zdroj: | Biosystems & Biorobotics ISBN: 9783319466682 3rd International Conference on NeuroRehabilitation ICNR: International Conference on NeuroRehabilitation ICNR: International Conference on NeuroRehabilitation, Oct 2016, Segovia, Spain. pp.731-735, ⟨10.1007/978-3-319-46669-9_120⟩ |
| DOI: | 10.1007/978-3-319-46669-9_120 |
| Popis: | International audience; Transversal intrafascicular multichannel electrodes (TIME) have been developed to interface with peripheral nerves after upper limb amputation. Intended use is the electrical stimulation of the median and ulnar nerve to deliver sensory feedback during phantom limb pain treatment and artificial hand control. Miniaturized electrode arrays were developed on polyimide substrates with thin film metallization using sputtered iridium oxide as electrode coating. Here, we report on the essential requirements including biocompatibility, mechanical and stimulation stability that have been investigated before permission was granted by the legal authorities to conduct subchronic first-in-man clinical trials. Explants have been investigated to identify possible first failure points and optimize the devices for chronic implantation. |
| Databáze: | OpenAIRE |
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