PULMONARY RHABDOMYOSARCOMA GENERATED DURING TREATMENT OF TESTICULAR TUMOR
| Autor: | Shigeo Kaneko, Hiroshi Hashimoto, Masafumi Kita, Sunao Yachiku, Fumiei Inada, Yutaka Sasaki, Mitsuhiko Okuyama, Hironori Ishida, Yuji Saga, Masayuki Tokumitsu |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Oncology medicine.medical_specialty Lung Neoplasms Urology medicine.medical_treatment VIP Regimen Drug Administration Schedule Embryonal carcinoma Retroperitoneal lymph node dissection Testicular Neoplasms Carcinoma Embryonal Internal medicine Antineoplastic Combined Chemotherapy Protocols Rhabdomyosarcoma medicine Humans Ifosfamide Pneumonectomy Cyclophosphamide Etoposide Chemotherapy business.industry Endodermal Sinus Tumor Seminoma medicine.disease Combined Modality Therapy Dacarbazine Doxorubicin Vincristine Lymph Node Excision Radiology Cisplatin business Orchiectomy medicine.drug |
| Zdroj: | The Japanese Journal of Urology. 94:696-700 |
| ISSN: | 1884-7110 0021-5287 |
| DOI: | 10.5980/jpnjurol1989.94.696 |
| Popis: | A 23-year-old male was admitted to our hospital for the management of pulmonary metastases. He had undergone right high orchiectomy, chemotherapy with four courses of PEB regimen (cisplatin, etoposide, bleomycin) and retroperitoneal lymph node dissection the previous year. The pathological findings showed mixed germ cell tumor (seminoma, yolk sac tumor, embryonal carcinoma) in the testis and mature teratoma in the draining lymph node. Two courses of salvage chemotherapy using a VIP regimen (etoposide, ifosfamide, cisplatin) were performed after diagnosis of pulmonary metastases, but had no affect on tumor size. Video-assisted excision of pulmonary metastases was then performed, giving a pathological diagnosis of rhabdomyosarcoma in all three resected tumors. The operation was followed by three courses of CYVADIC (cyclophosphamide, vincristine, adriamycin, dacarbazin) chemotherapy and oral cyclophosphamide, as a small residual tumor was suspected. These chemotherapeutic interventions have appeared effective, with no apparent recurrence of lesions at present, one year after the excision of pulmonary metastases. |
| Databáze: | OpenAIRE |
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