Haemodynamic Changes Associatedc with Obesity and High Blood Pressure in Crats with Ventromedial Hypothalamic Lesions
Autor: | Edward D. Frohlich, E. Reisin, Daniel H. Suarez |
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Rok vydání: | 1980 |
Předmět: |
Male
medicine.medical_specialty Cardiac output Hypothalamus Hemodynamics Kidney Plasma volume Essential hypertension Body weight Internal medicine medicine Animals Obesity Cardiac Output Plasma Volume business.industry Body Weight General Medicine medicine.disease Rats Hypothalamic lesion Blood pressure Endocrinology Hypertension business |
Zdroj: | Clinical Science. 59:397s-399s |
ISSN: | 0144-9664 |
DOI: | 10.1042/cs059397s |
Popis: | 1. The haemodynamic and plasma volume changes associated with obesity and high blood pressure were studied in nine male rats with electrolytic ventromedial hypothalamic lesions and their paired sham-operated controls. Body weight and arterial pressure were greater in the rats with ventromedial hypothalamic lesions (565 ± 16 vs 462 ± 14 g, P 2. The haemodynamic characteristics of rats in which obesity and mild hypertension have been induced by electrolytic ventromedial hypothalamic lesion are similar to mild obesity essential hypertension in men. |
Databáze: | OpenAIRE |
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