COVID-19 reinfection: the role of natural immunity, vaccines, and variants
| Autor: | Rohit Jain, Bao Y Sciscent, Lisa Ho, Reshma Golamari, Steven D King, Caroline D Eisele |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Innate immune system
COVID-19 vaccination Coronavirus disease 2019 (COVID-19) SARS-CoV-2 business.industry viruses Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) fungi COVID-19 virus diseases Review Article COVID-19 immunity Disease medicine.disease_cause RC31-1245 reinfection Death toll Pandemic Immunology Internal Medicine medicine Mass vaccination business Coronavirus |
| Zdroj: | Journal of Community Hospital Internal Medicine Perspectives article-version (VoR) Version of Record Journal of Community Hospital Internal Medicine Perspectives, Vol 11, Iss 6, Pp 733-739 (2021) |
| ISSN: | 2000-9666 |
| DOI: | 10.1080/20009666.2021.1974665 |
| Popis: | The COVID-19 pandemic has altered innumerable lives. Although recent mass vaccinations offer a glimmer of hope, the rising death toll and new variants continue to dominate the current scenario. As we begin to understand more about SARS-CoV-2 infections, the territory of reinfections with COVID-19 remains unexplored. In this review, we will discuss several aspects of reinfection: (a) How is COVID-19 reinfection characterized? (b) Does prior literature differentiate between reinfection and reactivation? (c) What SARS-CoV-2 strains do the vaccines target and can they protect against new strains? Larger and longer timeline studies are needed to understand reinfection risks. With the ongoing distribution of the SARS-CoV-2 vaccines to provide protection, the understanding of the possibility for SARS-CoV-2 reinfection remains critical. Abbreviations CDC: Centers for Disease ControlSARS-CoV-2: Severe acute respiratory syndrome coronavirus 2COVID-19: Coronavirus disease 2019RT-PCR: Reverse Transcription Polymerase Chain ReactionPASC: Post-Acute Sequelae of SARS-CoV-2 infection |
| Databáze: | OpenAIRE |
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