Electrostatic self-assembly of polysaccharides into nanofibers
| Autor: | Francisco M. Goycoolea, Timm Strohmenger, Ioannis S. Chronakis, Ana Carina Loureiro Mendes |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Nanofibers
02 engineering and technology 010402 general chemistry Polysaccharide 01 natural sciences Chitosan chemistry.chemical_compound Colloid and Surface Chemistry Polymer chemistry medicine Xanthan gum chemistry.chemical_classification Aqueous solution Self-assembly 021001 nanoscience & nanotechnology 0104 chemical sciences chemistry Ionic strength Nanofiber Drug delivery Chitosan oligomers 0210 nano-technology Polyssacharide medicine.drug |
| Zdroj: | Mendes, A C L, Strohmenger, T, Goycoolea, F & Chronakis, I S 2017, ' Electrostatic Self-Assembly of Polysaccharides into Nanofibers ', Colloids and Surfaces A: Physicochemical and Engineering Aspects, vol. 531, pp. 182-188 . https://doi.org/10.1016/j.colsurfa.2017.07.044 |
| ISSN: | 0927-7757 |
| Popis: | In this study, the anionic polysaccharide Xanthan gum (X) was mixed with positively charged Chitosan oligomers (ChO), and used as building blocks, to generate novel nanofibers by electrostatic self-assembly in aqueous conditions. Different concentrations, ionic strength and order of mixing of both components were tested and observed to affect the diameter, which ranged from 100 to 500 nm, and morphology of the self-assembled nanofibers. The release of diclofenac, as model drug, from self-assembled xanthan-chitosan nanofibers was demonstrated, suggesting that these nanostructures can be used in applications within life sciences such as drug delivery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect