Activation of chemical promutagens by Selenastrum capricornutum in the plant cell/microbe coincubation assay
| Autor: | J.M. Gentile, M. Lippert, T. Shafer, P. Johnson |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Salmonella typhimurium
Health Toxicology and Mutagenesis Microorganism Mutagen Selenastrum Phenylenediamines Toxicology medicine.disease_cause chemistry.chemical_compound Algae Cytochrome P-450 Enzyme System Aquatic plant Botany medicine Benzo(a)pyrene Bioassay biology Aquatic ecosystem fungi food and beverages Eukaryota General Medicine biology.organism_classification Pollution chemistry Biochemistry Xenobiotic Mutagens |
| Zdroj: | Bulletin of environmental contamination and toxicology. 44(5) |
| ISSN: | 0007-4861 |
| Popis: | The critical balance of organisms living in aquatic environments is influenced by the presence and relationship of plants to those environments. However, even though plants occupy a fundamental trophic level within aquatic ecosystems, few studies have focused upon the effect of xenobiotics on aquatic plants, and even fewer studies have dealt with xenobiotic metabolism by aquatic plants. It is well established that plants can metabolize chemicals into mutagens. The impact of these unique plant-activated chemical mutagens on ecosystems, food chains and, ultimately, human health is an important question that will require intensive and integrative investigation. The plant cell/microbe coincubation assay is particularly advantageous for use with unicellular algae. The conditions of this assay are such that chemical metabolism and subsequent mutagen detection can be followed in intact algal cells under simulated field conditions. The purpose of this research was to demonstrate that a unicellular algal species could be used effectively in the plant cell/microbe coincubation assay to activate model chemical mutagens. |
| Databáze: | OpenAIRE |
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