Chemoselective C-benzoylation of phenols by using AlCl3 under solvent-free conditions
| Autor: | Pradeep D. Lokhande, Sunil V. Gaikwad, Beena R. Nawghare |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Fries rearrangement
Solvent free Chemoselective C-acylation F-C reaction Fries rearrangement Aryl education Regioselectivity General Chemistry Chemoselective C-acylation Chloride humanities lcsh:Chemistry chemistry.chemical_compound chemistry lcsh:QD1-999 medicine Organic chemistry Phenols F-C reaction medicine.drug |
| Zdroj: | Bulletin of the Chemical Society of Ethiopia, Vol 29, Iss 2, Pp 319-325 (2015) Bulletin of the Chemical Society of Ethiopia; Vol 29, No 2 (2015); 319-325 |
| ISSN: | 1011-3924 1726-801X |
| Popis: | Substituted phenols were chemo-selectively reacted with benzoylchloride in presence of aluminum chloride under solvent-free condition to afford the corresponding 2'-hydroxy aryl benzophenones in excellent yields (72-96%). Naphthol benzoylation resulted in lower yields as compared to phenols. Both reactions completed in 5-10 min with quantitative yields providing excellent control over regioselectivity of products. KEY WORDS : Chemoselective C-acylation, F-C reaction, Fries rearrangement Bull. Chem. Soc. Ethiop. 2015 , 29(2), 319-325 DOI: http://dx.doi.org/10.4314/bcse.v29i2.14 |
| Databáze: | OpenAIRE |
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