A Case of Hypereosinophilic Syndrome Presenting With Multiorgan Infarctions Associated With Disseminated Intravascular Coagulation
| Autor: | Chul-Su Lee, Ji-Won Park, Eun-Hee Koo, Sun Mi Park, Dong-Chull Choi, Sung Min Kim, Byung Jae Lee, Jin Young Lee |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty interferon-alpha Immunology Alpha interferon Case Report Computed tomography Hypereosinophilic syndrome consumptive coagulopathy hemic and lymphatic diseases Internal medicine Consumptive Coagulopathy Immunology and Allergy Medicine Eosinophilia disseminated intravascular coagulation reproductive and urinary physiology Disseminated intravascular coagulation Intracerebral hemorrhage medicine.diagnostic_test business.industry thromboembolism medicine.disease Thrombosis Surgery Cardiology biological phenomena cell phenomena and immunity medicine.symptom business eosinophilia |
| Zdroj: | Allergy, Asthma & Immunology Research |
| ISSN: | 2092-7363 2092-7355 |
| DOI: | 10.4168/aair.2012.4.3.161 |
| Popis: | Thromboembolism is one of the most critical complications of hypereosinophilic syndrome (HES). We report here a case of multi-organ infarctions related to HES. A 23-year-old woman was referred to our hospital with hemoptysis. Not only pulmonary, but also renal and splenic infarctions were detected on computed tomography images. Blood tests showed profound peripheral eosinophilia. She was diagnosed with HES with disseminated intravascular coagulation (DIC). We initiated infusion of corticosteroids, which effectively suppressed peripheral eosinophilia. However, consumptive coagulopathy did not improve and intracerebral hemorrhage related to thrombosis then developed. Addition of interferon-alpha resulted in the correction of the DIC associated with HES. |
| Databáze: | OpenAIRE |
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