Predictors of atrial arrhythmias in patients with mitral valve prolapse
| Autor: | Yasin Türker, Gurkan Acar, Mustafa Özgül, Mehmet Ozaydin, Ercan Varol, Abdullah Dogan, Yeşim Hoşcan, Doğan Erdoğan |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Young Adult Risk Factors Internal medicine medicine Humans Mitral valve prolapse Heart rate variability cardiovascular diseases Isovolumetric contraction Aged Fibrillation Mitral regurgitation Mitral Valve Prolapse medicine.diagnostic_test business.industry Mitral Valve Insufficiency Arrhythmias Cardiac General Medicine Middle Aged medicine.disease Echocardiography Doppler C-Reactive Protein Logistic Models Electrocardiography Ambulatory cardiovascular system Cardiology Female Supraventricular tachycardia medicine.symptom Cardiology and Cardiovascular Medicine business Electrocardiography Atrial flutter |
| Zdroj: | Acta Cardiologica. 64:755-760 |
| ISSN: | 0001-5385 |
| DOI: | 10.2143/ac.64.6.2044739 |
| Popis: | Objective Arrhythmias have been reported to occur frequently in symptomatic patients with mitral valve prolapse (MVP). The mechanisms causing atrial arrhythmias in patients with MVP have not been fully investigated. The purpose of this study was to determine the clinical, echocardiographic and heart rate variability parameters, and plasma concentrations of electrolytes and inflammatory markers in predicting atrial arrhythmias in patients with MVP. Methods A total of 58 consecutive patients with MVP were included in this study. We performed electrocardiography, echocardiography, Holter analysis, routine biochemical tests including plasma concentrations of electrolytes and inflammatory markers, and evaluated the clinical characteristics. Atrial arrhythmia was defined as occurrence of any of the following: atrial premature contractions, atrial couplets, supraventricular tachycardia, atrial flutter or fibrillation documented by Holter analysis, continuous monitoring or by electrocardiography. Results Twenty-eight patients (48%) had atrial arrhythmias, and 30 (52%) patients had no atrial arrhythmias. Univariable predictors of atrial arrhythmias included isovolumetric relaxation time, lateral systolic (S'), lateral late diastolic (A'), septal A' Doppler velocities, anterior mitral leaflet thickness, anterior mitral leaflet thickness of > or =5 mm, posterior mitral leaflet thickness and the occurrence of moderate to severe mitral regurgitation. Multivariable logistic regression analysis showed that occurrence of moderate to severe mitral regurgitation was the only independent predictor of atrial arrhythmias (relative risk: 2.4, 95% confidence interval 1.32-4.86, P = 0.005). Conclusions The present study showed that the only independent predictor of atrial arrhythmias in patients with MVP is the occurrence of moderate to severe mitral regurgitation. |
| Databáze: | OpenAIRE |
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