Short-term evaluation of immune levels and nutritional values of EN versus PN in gastric cancer: a systematic review and a meta-analysis

Autor: Said Abdulrahman Salim Mzee, Chen Gong, Fan Xin, Godwin Botwe, Han He, Sun Zhiyu, Chen Jixing, Said Twahir Said
Rok vydání: 2019
Předmět:
Parenteral Nutrition
medicine.medical_specialty
Time Factors
PN
medicine.medical_treatment
lcsh:Surgery
Nutritional Status
Review
lcsh:RC254-282
Gastroenterology
law.invention
03 medical and health sciences
Enteral Nutrition
Postoperative Complications
0302 clinical medicine
Randomized controlled trial
Stomach Neoplasms
Gastrectomy
law
Internal medicine
medicine
Humans
ERAS
Feeding tube
Randomized Controlled Trials as Topic
Postoperative Care
business.industry
Retrospective cohort study
lcsh:RD1-811
Length of Stay
Prognosis
lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Immunity
Innate
Confidence interval
Treatment Outcome
Parenteral nutrition
Oncology
030220 oncology & carcinogenesis
Meta-analysis
Relative risk
030211 gastroenterology & hepatology
Surgery
EN feeding tubes
Gastric cancer
business
Nutritive Value
Zdroj: World Journal of Surgical Oncology, Vol 17, Iss 1, Pp 1-15 (2019)
World Journal of Surgical Oncology
ISSN: 1477-7819
DOI: 10.1186/s12957-019-1658-9
Popis: Background Postsurgical patients’ oral feeding begins with clear fluids 1–3 days after surgery. This might not be sufficiently nutritious to boost the host immune system and provide sufficient energy in gastric neoplastic patients to achieve the goal of enhanced recovery after surgery (ERAS). Our objective was to analyze the significance of early postoperative feeding tubes in boosting patients’ immunity and decreasing incidence of overall complications and hospital stay in gastric cancer patients’ post-gastrectomy. Methods From January 2005 to May 24, 2019, PubMed and Cochrane databases were searched for studies involving enteral nutrition (EN) feeding tubes in comparison to parenteral nutrition (PN) in gastric cancer patients undergoing gastrectomy for gastric malignancies. Relative risk (RR), mean difference (MD), or standard mean difference (SMD) with 95% confidence interval (CI) were used to estimate the effect sizes, and heterogeneity was assessed by using Q and χ 2 statistic with their corresponding P values. All the analyses were performed with Review Manager 5.3 and SPSS version 22. Results Nine randomized trials (n = 1437) and 5 retrospective studies (n = 421) comparing EN feeding tubes and PN were deemed eligible for the pooled analyses, with a categorized time frame of PODs ≥ 7 and PODs
Databáze: OpenAIRE
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